Breeding Rabbits is like clock-work. 29 days from the day you breed your Doe, she will have a litter of bunnies. You want to build a nesting box for the bunnies to be born in. Something enclosed with an edge in the doorway so they can't squirm out into the cage. Some signs to be aware of, showing the Doe is close to giving birth; She'll start pulling fur out and placing it in the box. Bring straw into box and create a nest out of it. You shouldn't mess with the nest once she starts.