Searching for the best hotels in Owensboro, Kentucky? We’re Family Destinations Guide, and we’re here to help: From upscale hotels in the heart of the city to charming boutique accommodations in local neighborhoods, and from top-rated luxury retreats to budget-friendly stays with nice views, we’ve got recommendations for every traveler. Whether you’re on a family vacation, a business trip, or a romantic getaway, click this now to discover the BEST places to stay in Owensboro, KY